As the European Union’s Health Technology Assessment Regulation (HTAR) came into effect in January 2025, the Annual HTA Conference in Greece, themed “HTA in Transition: Delivering Value Through Inclusive Health Policies” serves as a pivotal forum to explore the evolving landscape of health technology assessment. This year’s conference aims to address the multifaceted challenges and opportunities presented by the new regulation, emphasizing the importance of inclusive and collaborative approaches in health policy development. By bringing together diverse perspectives, the conference seeks to foster dialogue and share best practices, ensuring that the transition under the HTAR leads to more inclusive, efficient, and patient-centered health policies across Europe and Greece.